![Symtuza ([darunavir + cobicistat + emtricitabine + tenofovir alafenamide (TAF)]; Johnson & Johnson) Drug Overview 2019- Product Image](http://www.researchandmarkets.com/product_images/8219/8219245_500px_jpg/market_research_report.jpg)
Drug Overview
Symtuza ([darunavir + cobicistat + emtricitabine + tenofovir alafenamide (TAF)]; Johnson & Johnson) is a once-daily single-tablet regimen (STR) combination of the protease inhibitor (PI) Prezista, the two nucleos(t)ide reverse transcriptase inhibitors (NRTIs), Emtriva (emtricitabine; Gilead) and TAF (Gilead), and the boosting agent Tybost (cobicistat; Gilead). Symtuza is the first STR containing a PI.
While its convenience as a STR and the high resistance barrier of darunavir position Symtuza as a good alternative for treatment-experienced patients who have generated resistance to other regimens, it will struggle to compete in the first-line setting due to its late launch, generic threats, and fierce competition from Triumeq ([dolutegravir + abacavir + lamivudine]; ViiV Healthcare) and Biktarvy ([bictegravir + emtricitabine + TAF]; Gilead).
Symtuza ([darunavir + cobicistat + emtricitabine + tenofovir alafenamide (TAF)]; Johnson & Johnson) is a once-daily single-tablet regimen (STR) combination of the protease inhibitor (PI) Prezista, the two nucleos(t)ide reverse transcriptase inhibitors (NRTIs), Emtriva (emtricitabine; Gilead) and TAF (Gilead), and the boosting agent Tybost (cobicistat; Gilead). Symtuza is the first STR containing a PI.
While its convenience as a STR and the high resistance barrier of darunavir position Symtuza as a good alternative for treatment-experienced patients who have generated resistance to other regimens, it will struggle to compete in the first-line setting due to its late launch, generic threats, and fierce competition from Triumeq ([dolutegravir + abacavir + lamivudine]; ViiV Healthcare) and Biktarvy ([bictegravir + emtricitabine + TAF]; Gilead).
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